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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-12-22
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pubmed:abstractText |
The sarcomeric protein alpha actinin 3 is localised to the Z line of fast fibres, which are responsible for generating forceful muscle contractions at high velocity. However, a substantial proportion of healthy humans are totally deficient in this protein as they are homozygous for a premature stop codon polymorphism (R577X) in the ACTN3 gene. The purpose of this preliminary study was to assess if the presence or absence of alpha actinin 3 influences the deleterious effects of ageing on muscle output and functional capacity.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-10192379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-11085837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-11440986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-11753490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-11880821,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-11893790,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-12879365,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-14232808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-14555676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-15221860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-4044103,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-4188260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-4843734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-7556361,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-7925554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-8126356,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-8275048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-8458808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16371478-9094325
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1473-0480
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e1
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16371478-Actinin,
pubmed-meshheading:16371478-Aged,
pubmed-meshheading:16371478-Aged, 80 and over,
pubmed-meshheading:16371478-Aging,
pubmed-meshheading:16371478-Exercise Tolerance,
pubmed-meshheading:16371478-Female,
pubmed-meshheading:16371478-Humans,
pubmed-meshheading:16371478-Middle Aged,
pubmed-meshheading:16371478-Muscle, Skeletal,
pubmed-meshheading:16371478-Oxygen Consumption
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pubmed:year |
2006
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pubmed:articleTitle |
Does complete deficiency of muscle alpha actinin 3 alter functional capacity in elderly women? A preliminary report.
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pubmed:affiliation |
Universidad Europea de Madrid, Madrid, Spain.
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pubmed:publicationType |
Journal Article
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