| pubmed-article:16369537 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16369537 | lifeskim:mentions | umls-concept:C0019682 | lld:lifeskim |
| pubmed-article:16369537 | lifeskim:mentions | umls-concept:C0039195 | lld:lifeskim |
| pubmed-article:16369537 | lifeskim:mentions | umls-concept:C0042774 | lld:lifeskim |
| pubmed-article:16369537 | lifeskim:mentions | umls-concept:C0003316 | lld:lifeskim |
| pubmed-article:16369537 | lifeskim:mentions | umls-concept:C0599894 | lld:lifeskim |
| pubmed-article:16369537 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:16369537 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16369537 | pubmed:dateCreated | 2006-1-20 | lld:pubmed |
| pubmed-article:16369537 | pubmed:abstractText | Despite limited data supporting the superiority of dominant over subdominant responses, immunodominant epitopes represent the preferred vaccine candidates. To address the function of subdominant responses in human immunodeficiency virus infection, we analyzed cytotoxic T lymphocyte responses restricted by HLA-B*1503, a rare allele in a cohort infected with clade B, although common in one infected with clade C. HLA-B*1503 was associated with reduced viral loads in the clade B cohort but not the clade C cohort, although both shared the immunodominant response. Clade B viral control was associated with responses to several subdominant cytotoxic T lymphocyte epitopes, whereas their clade C variants were less well recognized. These data suggest that subdominant responses can contribute to in vivo viral control and that high HLA allele frequencies may drive the elimination of subdominant yet effective epitopes from circulating viral populations. | lld:pubmed |
| pubmed-article:16369537 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16369537 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16369537 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16369537 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16369537 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:16369537 | pubmed:issn | 1529-2908 | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:MullinsJames... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:MarincolaFran... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:AllenTodd MTM | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:CarringtonMar... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:WalkerBruce... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:LichterfeldMa... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:AddoMarylyn... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:FeeneyMargare... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:BranderChrist... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:GoulderPhilip... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:AltfeldMarcus... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:FrahmNicoleN | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:MallalSimonS | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:KorberBette... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:WurcelAlysse... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:MooreCoreyC | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:RoachTimothyT | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:PaeEuniceE | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:KiepielaPhoti... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:HeckermanDavi... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:St JohnM... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:AdamsSharonS | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:LindeCaitlyn... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:HewittHannah... | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:SangoKaoriK | lld:pubmed |
| pubmed-article:16369537 | pubmed:author | pubmed-author:LahaieMatthew... | lld:pubmed |
| pubmed-article:16369537 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16369537 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:16369537 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16369537 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16369537 | pubmed:pagination | 173-8 | lld:pubmed |
| pubmed-article:16369537 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:meshHeading | pubmed-meshheading:16369537... | lld:pubmed |
| pubmed-article:16369537 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16369537 | pubmed:articleTitle | Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. | lld:pubmed |
| pubmed-article:16369537 | pubmed:affiliation | Partners AIDS Research Center, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts 02115, USA. | lld:pubmed |
| pubmed-article:16369537 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16369537 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:16369537 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16369537 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16369537 | lld:pubmed |
