Source:http://linkedlifedata.com/resource/pubmed/id/16364861
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2005-12-20
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pubmed:abstractText |
Calcineurin inhibitor (CNI) immunosuppressants are a major cause of renal dysfunction in cardiac transplant recipients, leading to increased morbidity and mortality. The aim of this study was to evaluate the efficacy and safety of CNI withdrawal and substitution with sirolimus as the primary immunosuppressant, and assess the effect on renal function in cardiac transplant recipients with CNI-induced renal impairment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1557-3117
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2129-36
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16364861-Aged,
pubmed-meshheading:16364861-Calcineurin,
pubmed-meshheading:16364861-Female,
pubmed-meshheading:16364861-Graft Rejection,
pubmed-meshheading:16364861-Heart Transplantation,
pubmed-meshheading:16364861-Humans,
pubmed-meshheading:16364861-Immunosuppressive Agents,
pubmed-meshheading:16364861-Kidney,
pubmed-meshheading:16364861-Kidney Diseases,
pubmed-meshheading:16364861-Male,
pubmed-meshheading:16364861-Middle Aged,
pubmed-meshheading:16364861-Risk Factors,
pubmed-meshheading:16364861-Sirolimus
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pubmed:year |
2005
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pubmed:articleTitle |
Sirolimus in cardiac transplantation: use as a primary immunosuppressant in calcineurin inhibitor-induced nephrotoxicity.
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pubmed:affiliation |
Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA. kushwaha.sudhir@mayo.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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