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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2006-3-6
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pubmed:abstractText |
Different high-density lipoprotein (HDL) subclasses have distinct but interrelated metabolic functions. HDL directly influences the atherogenic process, and changes in HDL subclasses distribution may be related to the incidence and prevalence of atherosclerosis. Lipoprotein lipase (LPL) is an important enzyme for hydrolysis of triglyceride-rich lipoproteins, and its activity is positively correlated with the plasma HDL cholesterol level. LPL gene HindIII polymorphism has been found associated with variations in lipid levels, but the impact on HDL subclasses distribution is less clearly established.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
366
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
316-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16364275-Adult,
pubmed-meshheading:16364275-Aged,
pubmed-meshheading:16364275-Alleles,
pubmed-meshheading:16364275-Analysis of Variance,
pubmed-meshheading:16364275-Apolipoprotein A-I,
pubmed-meshheading:16364275-Binding Sites,
pubmed-meshheading:16364275-Cholesterol,
pubmed-meshheading:16364275-Cholesterol, HDL,
pubmed-meshheading:16364275-Deoxyribonuclease HindIII,
pubmed-meshheading:16364275-Female,
pubmed-meshheading:16364275-Gene Frequency,
pubmed-meshheading:16364275-Genotype,
pubmed-meshheading:16364275-Humans,
pubmed-meshheading:16364275-Hyperlipidemias,
pubmed-meshheading:16364275-Lipids,
pubmed-meshheading:16364275-Lipoprotein Lipase,
pubmed-meshheading:16364275-Lipoproteins, HDL,
pubmed-meshheading:16364275-Male,
pubmed-meshheading:16364275-Middle Aged,
pubmed-meshheading:16364275-Polymorphism, Genetic,
pubmed-meshheading:16364275-Triglycerides
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pubmed:year |
2006
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pubmed:articleTitle |
Relationship between plasma HDL subclasses distribution and lipoprotein lipase gene HindIII polymorphism in hyperlipidemia.
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pubmed:affiliation |
Apolipoprotein Research Unit, Department of Biochemistry and Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, 610041 Sichuan, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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