Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-12-19
pubmed:abstractText
In this study we evaluated the presence of patent foramen ovale (PFO) in a cohort of 25 consecutive patients suffering from migraine with aura (MA) during an attack presenting to the emergency ward of an Italian hospital. Patients underwent brain magnetic resonance imaging (MRI) with contrast medium, routine coagulation tests, contrast transcranial echocolour-coded sonography (c-TCCS) and transoesophageal echocardiography (TEE). Of the enrolled patients, 88.7% showed a PFO according to the c-TCCS test, whereas only in 72% TEE confirmed the presence of PFO. This discordance could be due to the fact that c-TCCS is more sensitive even with shunts with minimal capacity also located in the pulmonary vasculature. After surgical treatment of the PFO, MA disappeared within two months. Also, the treatment with warfarin as well as with acetylsalicylic acid and flunarizine was able to dramatically reduce the frequency of migraine attacks. These data indicate a higher prevalence of PFO in MA vs. normal population (OR=2.92) and could suggest that the presence of arteriovenous (AV) shunts could represent a trigger for MA attacks as well as for stroke, but more studies are needed to confirm this preliminary hypothesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1129-2369
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-6
pubmed:dateRevised
2008-2-6
pubmed:meshHeading
pubmed-meshheading:16362645-Adult, pubmed-meshheading:16362645-Anticoagulants, pubmed-meshheading:16362645-Brain, pubmed-meshheading:16362645-Calcium Channel Blockers, pubmed-meshheading:16362645-Cardiac Surgical Procedures, pubmed-meshheading:16362645-Cohort Studies, pubmed-meshheading:16362645-Cross-Sectional Studies, pubmed-meshheading:16362645-Echocardiography, Transesophageal, pubmed-meshheading:16362645-Female, pubmed-meshheading:16362645-Flunarizine, pubmed-meshheading:16362645-Heart Septal Defects, Atrial, pubmed-meshheading:16362645-Humans, pubmed-meshheading:16362645-Italy, pubmed-meshheading:16362645-Magnetic Resonance Imaging, pubmed-meshheading:16362645-Male, pubmed-meshheading:16362645-Middle Aged, pubmed-meshheading:16362645-Migraine with Aura, pubmed-meshheading:16362645-Predictive Value of Tests, pubmed-meshheading:16362645-Prevalence, pubmed-meshheading:16362645-Ultrasonography, Doppler, Transcranial
pubmed:year
2005
pubmed:articleTitle
High prevalence of patent foramen ovale in migraine with aura.
pubmed:affiliation
Centro Cefalee Alta Specialità, Dipartimento Area Critica, Reggio Emilia, Italy.
pubmed:publicationType
Journal Article, Case Reports