Source:http://linkedlifedata.com/resource/pubmed/id/16362265
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2006-5-23
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pubmed:abstractText |
Transplantation and replantation of the submandibular gland with microvascular techniques were demonstrated in a previous study, with good gland survival. The application of radiation on the neck bed was attempted to address an actual clinical scenario in this study. Five canine submandibular glands were transplanted using microvascular techniques to the ipsilateral femoral system. Radiotherapy at a dosage level of 3,600 cGy using 600 cGy q.d was delivered to the nasopharyngeal and neck regions 2 weeks after transplantation. The transferred glands were then reintroduced into the original but radiated neck bed. The glands were harvested for histological examination 8 weeks later. Four of five canine submandibular glands can withstand microvascular transplantation and then replantation into a radiated neck bed for at least 8 weeks. However, the salivary function was depleted. The canine submandibular gland can survive the transplantation and replantation for at least 8 weeks in spite of precipitating radiation insult on the neck bed for 3 weeks. Neurorraphy is, however, essential to maintaining the glandular function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0937-4477
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
263
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
490-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16362265-Animals,
pubmed-meshheading:16362265-Dogs,
pubmed-meshheading:16362265-Male,
pubmed-meshheading:16362265-Microsurgery,
pubmed-meshheading:16362265-Nasopharynx,
pubmed-meshheading:16362265-Neck,
pubmed-meshheading:16362265-Organ Transplantation,
pubmed-meshheading:16362265-Radiotherapy,
pubmed-meshheading:16362265-Replantation,
pubmed-meshheading:16362265-Submandibular Gland,
pubmed-meshheading:16362265-Time Factors,
pubmed-meshheading:16362265-Tissue and Organ Harvesting
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pubmed:year |
2006
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pubmed:articleTitle |
Microvascular transplantation and replantation of the dog submandibular gland.
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pubmed:affiliation |
Department of Otolaryngology and Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Neihu, Taipei, Taiwan. wfs19582001@mail.ndmctsgh.edu.tw
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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