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pubmed:abstractText |
Although single trisomy is the most common chromosomal abnormality observed within first trimester spontaneous abortions (SA) (>50%), double trisomy (DT) ranges from 0.21 to 2.8% in the literature. Since little is known about mechanisms underlying DT, we report the results of our experience with 517 SA, establishing parental origin and cell stage of non-disjunction when possible in DT cases, and making a revision of those previously reported.
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pubmed:affiliation |
Human Genetics, Fundacion Jimenez Diaz, Avda Reyes Católicos 2, 28040, Madrid, Spain. ddiego@fjd.es
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