16357316

Source:http://linkedlifedata.com/resource/pubmed/id/16357316

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007226, umls-concept:C0017296, umls-concept:C0037083, umls-concept:C0086418, umls-concept:C0225336, umls-concept:C0442335, umls-concept:C1280500
pubmed:issue	3
pubmed:dateCreated	2006-2-17
pubmed:abstractText	Endothelium is an important target for gene therapy. We have investigated the effect of viral and nonviral vectors on the phenotype and function of endothelial cells (ECs) and developed methods to block any activation caused by these vectors.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9505803
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	1524-4636
pubmed:author	pubmed-author:AlamA K M ShamsulAK, pubmed-author:BeutelspacherSven CSC, pubmed-author:FazekasovaHenrietaH, pubmed-author:GeorgeAndrew J TAJ, pubmed-author:ManuntaMariaM, pubmed-author:McClureMyra OMO, pubmed-author:TanPeng HPH, pubmed-author:XueShao-AnSA
pubmed:issnType	Electronic
pubmed:volume	26
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	462-7
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:16357316-Adenoviridae, pubmed-meshheading:16357316-Cardiovascular Diseases, pubmed-meshheading:16357316-Cell Adhesion, pubmed-meshheading:16357316-Cell Movement, pubmed-meshheading:16357316-Cells, Cultured, pubmed-meshheading:16357316-Cytokines, pubmed-meshheading:16357316-Endothelium, Vascular, pubmed-meshheading:16357316-Gene Therapy, pubmed-meshheading:16357316-Genetic Vectors, pubmed-meshheading:16357316-Humans, pubmed-meshheading:16357316-Lentivirus, pubmed-meshheading:16357316-Moloney murine leukemia virus, pubmed-meshheading:16357316-Phenotype, pubmed-meshheading:16357316-Phosphatidylinositol 3-Kinases, pubmed-meshheading:16357316-Proto-Oncogene Proteins c-akt, pubmed-meshheading:16357316-Saphenous Vein, pubmed-meshheading:16357316-Signal Transduction, pubmed-meshheading:16357316-Th1 Cells, pubmed-meshheading:16357316-Transduction, Genetic, pubmed-meshheading:16357316-Vasculitis
pubmed:year	2006
pubmed:articleTitle	Effect of vectors on human endothelial cell signal transduction: implications for cardiovascular gene therapy.
pubmed:affiliation	Division of Medicine, Department of Immunology, Imperial College London, Hammersmith Hospital, London, UK. ptan@imperial.ac.uk
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't