|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006376,
umls-concept:C0034656,
umls-concept:C0043210,
umls-concept:C0177804,
umls-concept:C0232970,
umls-concept:C0243127,
umls-concept:C0262950,
umls-concept:C0339510,
umls-concept:C0354100,
umls-concept:C0442805,
umls-concept:C0443331,
umls-concept:C0547047,
umls-concept:C0681867,
umls-concept:C0917713,
umls-concept:C1274040,
umls-concept:C1414083,
umls-concept:C1826421,
umls-concept:C2699549
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|
pubmed:issue |
1
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|
pubmed:dateCreated |
2005-12-15
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|
pubmed:abstractText |
To study effects of loop diuretics on bone, 87 women were randomized to 1 year of treatment with bumetanide or placebo. Compared with placebo, bumetanide decreased BMD by 2% at the total hip and by 1.4% at the whole body. Levels of biochemical bone markers were lower in the placebo than in the bumetanide group. Thus, treatment with loop diuretics affects bone metabolism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0884-0431
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16355285-Aged,
pubmed-meshheading:16355285-Bone Density,
pubmed-meshheading:16355285-Bone Remodeling,
pubmed-meshheading:16355285-Bumetanide,
pubmed-meshheading:16355285-Calcium,
pubmed-meshheading:16355285-Diuretics,
pubmed-meshheading:16355285-Female,
pubmed-meshheading:16355285-Fractures, Bone,
pubmed-meshheading:16355285-Humans,
pubmed-meshheading:16355285-Middle Aged,
pubmed-meshheading:16355285-Osteoporosis, Postmenopausal,
pubmed-meshheading:16355285-Risk Factors,
pubmed-meshheading:16355285-Time Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Loop diuretics increase bone turnover and decrease BMD in osteopenic postmenopausal women: results from a randomized controlled study with bumetanide.
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pubmed:affiliation |
Department of Endocrinology and Metabolism C, Aarhus Sygehus, Aarhus University Hospital, Aarhus, Denmark. rejnmark@post6.tele.dk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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