Source:http://linkedlifedata.com/resource/pubmed/id/16351191
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2005-12-14
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pubmed:abstractText |
Photodynamic therapy (PDT) for exudative age-related macular degeneration (AMD) was evaluated using a supramolecular nanomedical device, that is, a novel dendritic photosensitizer (DP) encapsulated by a polymeric micelle formulation. The characteristic dendritic structure of the DP prevents aggregation of its core sensitizer, thereby inducing a highly effective photochemical reaction. With its highly selective accumulation on choroidal neovascularization (CNV) lesions, this treatment resulted in a remarkably efficacious CNV occlusion with minimal unfavorable phototoxicity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1530-6984
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pubmed:author |
pubmed-author:AidaTakuzoT,
pubmed-author:HaradaAtsushiA,
pubmed-author:IdetaRyuichiR,
pubmed-author:JangWoo-DongWD,
pubmed-author:KataokaKazunoriK,
pubmed-author:NishiyamaNobuhiroN,
pubmed-author:TamakiYasuhiroY,
pubmed-author:TasakaFumitakaF,
pubmed-author:YanagiYasuoY,
pubmed-author:ZhangGuo-DongGD
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2426-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16351191-Animals,
pubmed-meshheading:16351191-Drug Carriers,
pubmed-meshheading:16351191-Glaucoma, Neovascular,
pubmed-meshheading:16351191-Macromolecular Substances,
pubmed-meshheading:16351191-Male,
pubmed-meshheading:16351191-Nanotechnology,
pubmed-meshheading:16351191-Photochemotherapy,
pubmed-meshheading:16351191-Photosensitizing Agents,
pubmed-meshheading:16351191-Porphyrins,
pubmed-meshheading:16351191-Rats
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pubmed:year |
2005
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pubmed:articleTitle |
Nanotechnology-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer.
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pubmed:affiliation |
Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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