Source:http://linkedlifedata.com/resource/pubmed/id/16344925
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-1-26
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pubmed:abstractText |
The human placenta is a complex organ situated at the interface between mother and foetus that separates maternal from foetal blood. The placental surfaces exposed to the two bloodstreams are different, i.e. trophoblasts and endothelial cells are in contact with the maternal and foetal circulation, respectively. Both cell types produce high insulin receptor levels. The aim of the present study was to test the hypothesis that spatio-temporal changes in insulin receptor expression in trophoblasts from first trimester to the endothelium at term shift the control of insulin-dependent processes from mother to foetus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0012-186X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
123-31
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16344925-Blood Circulation,
pubmed-meshheading:16344925-Endothelium, Vascular,
pubmed-meshheading:16344925-Female,
pubmed-meshheading:16344925-Fetal Blood,
pubmed-meshheading:16344925-Fetal Development,
pubmed-meshheading:16344925-Gene Expression Regulation,
pubmed-meshheading:16344925-Gestational Age,
pubmed-meshheading:16344925-Humans,
pubmed-meshheading:16344925-Infant, Newborn,
pubmed-meshheading:16344925-Insulin,
pubmed-meshheading:16344925-Maternal-Fetal Exchange,
pubmed-meshheading:16344925-Placenta,
pubmed-meshheading:16344925-Pregnancy,
pubmed-meshheading:16344925-Trophoblasts
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pubmed:year |
2006
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pubmed:articleTitle |
Insulin control of placental gene expression shifts from mother to foetus over the course of pregnancy.
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pubmed:affiliation |
Clinic of Obstetrics and Gynecology, Medical University of Graz, Auenbruggerplatz 14, 8036 Graz, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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