rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2006-3-6
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pubmed:abstractText |
Atherosclerosis has been considered to be an inflammatory process. In addition to its lipid-lowering properties, statin has been shown to decrease the concentrations of inflammatory markers resulting in reduction of cardiovascular events. Emerging data suggest that withdrawal of statin might be associated with increased cardiac events. The mechanism for this phenomenon, however, is still unclear. We investigated whether acute termination of statin treatment could result in rebound of inflammatory markers, such as C-reactive protein (CRP) and interleukin-6 (IL-6), in patients with hyperlipidemia.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0009-8981
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
366
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-73
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16343471-Adult,
pubmed-meshheading:16343471-Analysis of Variance,
pubmed-meshheading:16343471-Anticholesteremic Agents,
pubmed-meshheading:16343471-Biological Markers,
pubmed-meshheading:16343471-C-Reactive Protein,
pubmed-meshheading:16343471-Cholesterol, LDL,
pubmed-meshheading:16343471-Female,
pubmed-meshheading:16343471-Humans,
pubmed-meshheading:16343471-Hyperlipidemias,
pubmed-meshheading:16343471-Interleukin-6,
pubmed-meshheading:16343471-Lipids,
pubmed-meshheading:16343471-Male,
pubmed-meshheading:16343471-Middle Aged,
pubmed-meshheading:16343471-Pravastatin,
pubmed-meshheading:16343471-Time Factors,
pubmed-meshheading:16343471-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Changes of plasma inflammatory markers after withdrawal of statin therapy in patients with hyperlipidemia.
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pubmed:affiliation |
Department of Cardiology, Fu Wai Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beilishi Road 167, Beijing 100037, People's Republic of China. lijnjn@yahoo.com.cn
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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