Source:http://linkedlifedata.com/resource/pubmed/id/16342923
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2005-12-13
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pubmed:abstractText |
In fitting regression models, data analysts must often choose a model based on several candidate predictor variables which may influence the outcome. Most analysts either assume a linear relationship for continuous predictors, or categorize them and postulate step functions. By contrast, we propose to model possible non-linearity in the relationship between the outcome and several continuous predictors by estimating smooth functions of the predictors. We aim to demonstrate that a structured approach based on fractional polynomials can give a broadly satisfactory practical solution to the problem of simultaneously identifying a subset of 'important' predictors and determining the functional relationship for continuous predictors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0026-1270
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
561-71
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pubmed:meshHeading |
pubmed-meshheading:16342923-Algorithms,
pubmed-meshheading:16342923-Computer Simulation,
pubmed-meshheading:16342923-Epidemiologic Research Design,
pubmed-meshheading:16342923-Humans,
pubmed-meshheading:16342923-Models, Statistical,
pubmed-meshheading:16342923-Prognosis,
pubmed-meshheading:16342923-Proportional Hazards Models,
pubmed-meshheading:16342923-Regression Analysis,
pubmed-meshheading:16342923-Risk Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Building multivariable regression models with continuous covariates in clinical epidemiology--with an emphasis on fractional polynomials.
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pubmed:affiliation |
Cancer Division, MRC Clinical Trials Unit, London, UK. patrick.royston@ctu.mrc.ac.uk
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pubmed:publicationType |
Journal Article
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