Source:http://linkedlifedata.com/resource/pubmed/id/16336953
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-1-20
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pubmed:abstractText |
We hypothesized that modification of the infusion route may improve the efficiency of superoxide dismutase (SOD)-induced cardioprotection against reperfusion injury. The routes for SOD delivery previously examined were intravenous, via the left atrium, or by a combination of these, all of which can deliver SOD into the ischemic myocardium only after reperfusion. In contrast, retrograde intracoronary infusion may be able to deliver SOD before reperfusion. We investigated the feasibility and efficiency of the retrograde intracoronary infusion of SOD to attenuate reperfusion injury.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-6363
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
459-65
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16336953-Animals,
pubmed-meshheading:16336953-Coronary Circulation,
pubmed-meshheading:16336953-Coronary Vessels,
pubmed-meshheading:16336953-Echocardiography,
pubmed-meshheading:16336953-Free Radical Scavengers,
pubmed-meshheading:16336953-Infusions, Intravenous,
pubmed-meshheading:16336953-Male,
pubmed-meshheading:16336953-Models, Animal,
pubmed-meshheading:16336953-Myocardial Ischemia,
pubmed-meshheading:16336953-Myocardial Reperfusion Injury,
pubmed-meshheading:16336953-Rats,
pubmed-meshheading:16336953-Rats, Inbred Lew,
pubmed-meshheading:16336953-Superoxide Dismutase,
pubmed-meshheading:16336953-Ventricular Dysfunction, Left
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pubmed:year |
2006
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pubmed:articleTitle |
Enhanced efficiency of superoxide dismutase-induced cardioprotection by retrograde intracoronary administration.
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pubmed:affiliation |
Cell and Gene Therapy Group, Harefield Heart Science Centre, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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