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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2005-12-7
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pubmed:abstractText |
A recent single-center multivariate analysis of hepatitis C (HCV) patients showed that having any two criteria: 1) ferritin > or =200 microg/l and 2) spider nevi and/or albumin < or = 35 g/l predicted grade 2 or greater histological inflammation; the presence of any two of the following criteria: spider nevi, platelets < or =150 x 109/l, palpable splenomegaly and/or albumin < or =35 g/l predicted stage 2 or greater histological fibrosis. Absence of predictors also predicted a lack of inflammation and fibrosis. Our aim was prospectively to validate this clinical prediction model using an independent multicenter sample.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0036-5521
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1365-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16334447-Adult,
pubmed-meshheading:16334447-Aged,
pubmed-meshheading:16334447-Alanine Transaminase,
pubmed-meshheading:16334447-Biopsy, Needle,
pubmed-meshheading:16334447-Confidence Intervals,
pubmed-meshheading:16334447-Disease Progression,
pubmed-meshheading:16334447-Female,
pubmed-meshheading:16334447-Follow-Up Studies,
pubmed-meshheading:16334447-Hepatitis C, Chronic,
pubmed-meshheading:16334447-Humans,
pubmed-meshheading:16334447-Immunohistochemistry,
pubmed-meshheading:16334447-Liver Cirrhosis,
pubmed-meshheading:16334447-Liver Function Tests,
pubmed-meshheading:16334447-Male,
pubmed-meshheading:16334447-Middle Aged,
pubmed-meshheading:16334447-Physical Examination,
pubmed-meshheading:16334447-Predictive Value of Tests,
pubmed-meshheading:16334447-Prospective Studies,
pubmed-meshheading:16334447-ROC Curve,
pubmed-meshheading:16334447-Risk Assessment,
pubmed-meshheading:16334447-Sensitivity and Specificity,
pubmed-meshheading:16334447-Severity of Illness Index
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pubmed:year |
2005
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pubmed:articleTitle |
Simple clinical variables predict liver histology in hepatitis C: prospective validation of a clinical prediction model.
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pubmed:affiliation |
Digestive Disease Center, University of South Carolina, 96 Jonathon Lucas Street, PO Box 250 327, Charleston, SC 29425, USA. romagnuo@musc.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Validation Studies
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