|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2006-3-8
|
|
pubmed:abstractText |
The mechanisms driving steroid production in aldosterone-producing adenomas (APAs) are poorly defined. However, previous studies have shown that steroid production in some cortisol-producing adenomas is regulated by aberrant expression of G protein-coupled receptors. Aberrant adrenal expression of LH receptors has been shown to cause Cushing's syndrome, but the role of LH receptors in Conn's disease (hyperaldosteronism) has not been studied.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0021-972X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
91
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1136-42
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:16332935-Adenoma,
pubmed-meshheading:16332935-Adrenal Cortex Neoplasms,
pubmed-meshheading:16332935-Adrenal Glands,
pubmed-meshheading:16332935-Aldosterone,
pubmed-meshheading:16332935-Corpus Luteum,
pubmed-meshheading:16332935-DNA Primers,
pubmed-meshheading:16332935-Female,
pubmed-meshheading:16332935-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16332935-Humans,
pubmed-meshheading:16332935-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16332935-Ovarian Follicle,
pubmed-meshheading:16332935-Plasmids,
pubmed-meshheading:16332935-RNA, Messenger,
pubmed-meshheading:16332935-Receptors, LH,
pubmed-meshheading:16332935-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16332935-Transfection,
pubmed-meshheading:16332935-Tumor Cells, Cultured
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Elevated expression of luteinizing hormone receptor in aldosterone-producing adenomas.
|
|
pubmed:affiliation |
Department of Physiology, Medical College of Georgia, 1120 15th Street, Augusta, Georgia 30912, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
