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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-2-7
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pubmed:abstractText |
The reproductive endocrinology in Asians and Caucasians is of great interest in view of large differences in prostate cancer rate and sensitivity to pharmacological male contraception. In addition, interpretation of certain antidoping tests is confounded by interethnic variation in androgen disposition. Uridine diphosphoglucuronosyl transferases have a key role in the homeostasis and metabolism of androgens. Recently a deletion polymorphism was detected in the UGT2B17 gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0021-972X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
687-93
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16332934-Adolescent,
pubmed-meshheading:16332934-Adult,
pubmed-meshheading:16332934-Asian Continental Ancestry Group,
pubmed-meshheading:16332934-DNA,
pubmed-meshheading:16332934-European Continental Ancestry Group,
pubmed-meshheading:16332934-Genotype,
pubmed-meshheading:16332934-Glucuronosyltransferase,
pubmed-meshheading:16332934-Humans,
pubmed-meshheading:16332934-Hydroxyprogesterones,
pubmed-meshheading:16332934-Korea,
pubmed-meshheading:16332934-Male,
pubmed-meshheading:16332934-Mutation,
pubmed-meshheading:16332934-Polymerase Chain Reaction,
pubmed-meshheading:16332934-Polymorphism, Genetic,
pubmed-meshheading:16332934-Sex Hormone-Binding Globulin,
pubmed-meshheading:16332934-Statistics, Nonparametric,
pubmed-meshheading:16332934-Sweden,
pubmed-meshheading:16332934-Testosterone
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pubmed:year |
2006
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pubmed:articleTitle |
Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism.
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pubmed:affiliation |
Clinical Pharmacology, C1:68, Karolinska Institutet at Karolinska University Hospital, S-141 86 Stockholm, Sweden. jenny.jakobsson@ki.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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