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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-3-10
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pubmed:abstractText |
With the advent of replication competent viruses for cancer gene therapy, it has become imperative to monitor the biodistribution, expression and replication of these vectors in living organisms. We evaluated the potential of I-124 positron emission tomography (PET)/computed tomography (CT) imaging in gene therapy animal models utilizing the sodium iodide symporter (NIS) and compared the findings to I-123 gamma camera imaging.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1536-1632
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16328647-Animals,
pubmed-meshheading:16328647-Cell Line, Tumor,
pubmed-meshheading:16328647-Female,
pubmed-meshheading:16328647-Gene Expression,
pubmed-meshheading:16328647-Gene Transfer Techniques,
pubmed-meshheading:16328647-Genetic Vectors,
pubmed-meshheading:16328647-Humans,
pubmed-meshheading:16328647-Iodine Radioisotopes,
pubmed-meshheading:16328647-Mice,
pubmed-meshheading:16328647-Mice, SCID,
pubmed-meshheading:16328647-Models, Animal,
pubmed-meshheading:16328647-Neoplasm Transplantation,
pubmed-meshheading:16328647-Positron-Emission Tomography,
pubmed-meshheading:16328647-Radiopharmaceuticals,
pubmed-meshheading:16328647-Symporters,
pubmed-meshheading:16328647-Tomography, X-Ray Computed,
pubmed-meshheading:16328647-Transfection,
pubmed-meshheading:16328647-Transplantation, Heterologous
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pubmed:articleTitle |
Combined I-124 positron emission tomography/computed tomography imaging of NIS gene expression in animal models of stably transfected and intravenously transfected tumor.
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pubmed:affiliation |
Molecular Medicine Program, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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