Source:http://linkedlifedata.com/resource/pubmed/id/16324892
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2006-1-30
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pubmed:abstractText |
For a microdialytic trapping method we systematically investigated changes in concentrations of 2,5-dihydroxy-benzoic acid (2,5-DHBA) and 2,3-dihydroxy-benzoic acid (2,3-DHBA) in freshly prepared solutions of salicylic acid (SA). The solvent was 0.9% saline exposed to different atmospheric concentrations of oxygen (0, 21, and 100%). The solutions were treated by freezing-thawing and an ultrasonic bath in presence and absence of aluminium foil. Without aluminium the concentrations of 2,5-DHBA and 2,3-DHBA kept constant over an observed period of 160 min on different levels from below 20 ng/ml to about 100 ng/ml. In presence of aluminium the concentrations increased to maximum 307 ng/ml after 160 min. Ultrasonic irradiation amplified this effect to maximum 341 ng/ml. HPLC/ECD processing and quantitative analysis of dihydroxy-benzoic acids (DHBAs) in microdialysis may be artificially influenced by varying oxygen environment and metal catalysis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3-dihydroxy benzoic acid,
http://linkedlifedata.com/resource/pubmed/chemical/2,5-dihydroxybenzoic acid,
http://linkedlifedata.com/resource/pubmed/chemical/Aluminum,
http://linkedlifedata.com/resource/pubmed/chemical/Catechols,
http://linkedlifedata.com/resource/pubmed/chemical/Gentisates,
http://linkedlifedata.com/resource/pubmed/chemical/Metals,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen,
http://linkedlifedata.com/resource/pubmed/chemical/Salicylic Acid
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1570-0232
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
831
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
320-3
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pubmed:meshHeading |
pubmed-meshheading:16324892-Aluminum,
pubmed-meshheading:16324892-Catalysis,
pubmed-meshheading:16324892-Catechols,
pubmed-meshheading:16324892-Chromatography, Liquid,
pubmed-meshheading:16324892-Gentisates,
pubmed-meshheading:16324892-Metals,
pubmed-meshheading:16324892-Microdialysis,
pubmed-meshheading:16324892-Oxidation-Reduction,
pubmed-meshheading:16324892-Oxygen,
pubmed-meshheading:16324892-Salicylic Acid,
pubmed-meshheading:16324892-Time Factors
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pubmed:year |
2006
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pubmed:articleTitle |
The salicylate trapping method: is oxidation of salicylic acid solution oxygen and time dependent and metal catalysed?
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pubmed:affiliation |
Department of Anaesthesiology, University of Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg 93053, Germany. Michael.Gruber@klinik.uni-regensburg.de
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pubmed:publicationType |
Journal Article
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