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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2006-1-30
pubmed:abstractText
For a microdialytic trapping method we systematically investigated changes in concentrations of 2,5-dihydroxy-benzoic acid (2,5-DHBA) and 2,3-dihydroxy-benzoic acid (2,3-DHBA) in freshly prepared solutions of salicylic acid (SA). The solvent was 0.9% saline exposed to different atmospheric concentrations of oxygen (0, 21, and 100%). The solutions were treated by freezing-thawing and an ultrasonic bath in presence and absence of aluminium foil. Without aluminium the concentrations of 2,5-DHBA and 2,3-DHBA kept constant over an observed period of 160 min on different levels from below 20 ng/ml to about 100 ng/ml. In presence of aluminium the concentrations increased to maximum 307 ng/ml after 160 min. Ultrasonic irradiation amplified this effect to maximum 341 ng/ml. HPLC/ECD processing and quantitative analysis of dihydroxy-benzoic acids (DHBAs) in microdialysis may be artificially influenced by varying oxygen environment and metal catalysis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1570-0232
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
831
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
320-3
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
The salicylate trapping method: is oxidation of salicylic acid solution oxygen and time dependent and metal catalysed?
pubmed:affiliation
Department of Anaesthesiology, University of Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg 93053, Germany. Michael.Gruber@klinik.uni-regensburg.de
pubmed:publicationType
Journal Article