Source:http://linkedlifedata.com/resource/pubmed/id/16315878
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
2005-11-30
|
pubmed:abstractText |
The immunological functions of Ganoderma lucidum antlered form (AF) (Rokkaku-Reishi in Japanese), a variant type of Ganoderma lucidum, were investigated in C57BL/6 mice treated with cyclophosphamide (CY). Ganoderma lucidum AF alleviated CY-induced decrease in body weight and abnormal increase in blood neutrophil level, when the mice were fed a diet containing 2.5% Ganoderma lucidum AF starting one week before CY treatment (150 mg/kg, ip). The recovery of CD8+ and NK1.1+ cells in the spleen was accelerated in Ganoderma lucidum AF group compared to the control group. Ganoderma lucidum AF also both alleviated CY-induced splenic lymphopenia and suppressed the abnormal increase in splenocytes 7 days after CY treatment. These results suggest that ingestion of Ganoderma lucidum AF is beneficial for improvement of quality of life reduced by anti-cancer chemotherapeutic drugs such as CY.
|
pubmed:language |
jpn
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0385-0684
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1586-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16315878-Administration, Oral,
pubmed-meshheading:16315878-Animals,
pubmed-meshheading:16315878-Antineoplastic Agents, Alkylating,
pubmed-meshheading:16315878-Body Weight,
pubmed-meshheading:16315878-Cyclophosphamide,
pubmed-meshheading:16315878-Drugs, Chinese Herbal,
pubmed-meshheading:16315878-Leukocyte Count,
pubmed-meshheading:16315878-Male,
pubmed-meshheading:16315878-Mice,
pubmed-meshheading:16315878-Mice, Inbred C57BL,
pubmed-meshheading:16315878-Neutrophils
|
pubmed:year |
2005
|
pubmed:articleTitle |
[Soothing effect of Ganoderma lucidum antlered form on cyclophosphamide-induced adverse reaction].
|
pubmed:affiliation |
Institute for Health Care Science, Suntory Ltd.
|
pubmed:publicationType |
Journal Article,
English Abstract
|