|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006901,
umls-concept:C0009498,
umls-concept:C0017262,
umls-concept:C0056195,
umls-concept:C0185117,
umls-concept:C0333562,
umls-concept:C0403592,
umls-concept:C0596790,
umls-concept:C1514468,
umls-concept:C1534709,
umls-concept:C2718314,
umls-concept:C2911684
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2005-11-29
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|
pubmed:abstractText |
Chronic allograft nephropathy (CAN), associated with late-allograft dysfunction is caused by alloantigen-dependent and -independent mechanisms, and eventually leads to interstitial fibrosis (ci). Activation of complement cascade is considered to be a poor prognostic marker of graft survival. This study was designed to examine the relationship between the expression of C4d and heat-shock protein 47 (HSP47, a collagen-specific chaperone) in the development of interstitial fibroproliferative lesions in CAN.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0902-0063
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
810-6
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pubmed:meshHeading |
pubmed-meshheading:16313330-Adolescent,
pubmed-meshheading:16313330-Adult,
pubmed-meshheading:16313330-Capillaries,
pubmed-meshheading:16313330-Complement C4b,
pubmed-meshheading:16313330-Endothelium, Vascular,
pubmed-meshheading:16313330-Female,
pubmed-meshheading:16313330-Graft Rejection,
pubmed-meshheading:16313330-HSP47 Heat-Shock Proteins,
pubmed-meshheading:16313330-Humans,
pubmed-meshheading:16313330-Immunohistochemistry,
pubmed-meshheading:16313330-Kidney Cortex,
pubmed-meshheading:16313330-Kidney Diseases,
pubmed-meshheading:16313330-Kidney Transplantation,
pubmed-meshheading:16313330-Kidney Tubules,
pubmed-meshheading:16313330-Male,
pubmed-meshheading:16313330-Middle Aged,
pubmed-meshheading:16313330-Peptide Fragments,
pubmed-meshheading:16313330-Transplantation, Homologous
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Interstitial expression of heat-shock protein 47 correlates with capillary deposition of complement split product C4d in chronic allograft nephropathy.
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|
pubmed:affiliation |
Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
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pubmed:publicationType |
Journal Article
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