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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-1-10
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pubmed:abstractText |
Several studies reported that prolongation of overall treatment time of fractionated radiotherapy reduces the chance of tumor control. In the present study, we hypothesize that combining topotecan with irradiation could compensate for this detrimental time effect on the radioresponse. Therefore, we investigated the efficiency of different schedules of topotecan (TPT), radiotherapy (RT) or concomitant combination TPT + RT.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0167-594X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16311843-Animals,
pubmed-meshheading:16311843-Antineoplastic Agents,
pubmed-meshheading:16311843-Brain Neoplasms,
pubmed-meshheading:16311843-Combined Modality Therapy,
pubmed-meshheading:16311843-Disease Progression,
pubmed-meshheading:16311843-Dose-Response Relationship, Radiation,
pubmed-meshheading:16311843-Drug Administration Schedule,
pubmed-meshheading:16311843-Female,
pubmed-meshheading:16311843-Glioma,
pubmed-meshheading:16311843-Humans,
pubmed-meshheading:16311843-Mice,
pubmed-meshheading:16311843-Mice, Nude,
pubmed-meshheading:16311843-Topotecan,
pubmed-meshheading:16311843-Transplantation, Heterologous
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pubmed:year |
2006
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pubmed:articleTitle |
Topotecan can compensate for protracted radiation treatment time effects in high grade glioma xenografts.
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pubmed:affiliation |
Laboratoire de Recherche en Oncologie, Centre A. Vautrin, Vandoeuvre-lès-Nancy, France. pinel.sophie@tiscali.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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