Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2005-11-28
pubmed:abstractText
Behavioral and psychological symptoms of dementia (BPSD), constitute a major clinical component of Alzheimer's disease (AD). There is a growing interest in BPSD as they are responsible for a large share of the suffering of patients and caregivers, and they strongly determine the patient's lifestyle and management. Better detection and understanding of these symptoms is essential to provide appropriate management. This article is a consensus produced by the behavioral group of the European Alzheimer's Disease Consortium (EADC). The aim of this article is to present clinical description and biological correlates of the major behavioral and psychological symptomatology in AD. BPSD is not a unitary concept. Instead, it should be divided into several symptoms or more likely: groups of symptoms, each possibly reflecting a different prevalence, course over time, biological correlate and psychosocial determinants. There is some clinical evidence for clusters within groups of BPSD. Biological studies indicate that patients with AD and BPSD are associated with variations in the pathological features (atrophy, brain perfusion/metabolism, histopathology) when compared to people with AD without BPSD. An individually tailored approach taking all these aspects into account is warranted as it may offer more, and better, pharmacological and non-pharmacological treatment opportunities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0924-9338
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
490-6
pubmed:meshHeading
pubmed-meshheading:16310680-Aged, pubmed-meshheading:16310680-Aggression, pubmed-meshheading:16310680-Alzheimer Disease, pubmed-meshheading:16310680-Brain, pubmed-meshheading:16310680-Cerebrovascular Circulation, pubmed-meshheading:16310680-Cognition Disorders, pubmed-meshheading:16310680-Consensus, pubmed-meshheading:16310680-Dementia, pubmed-meshheading:16310680-Europe, pubmed-meshheading:16310680-Evoked Potentials, pubmed-meshheading:16310680-Female, pubmed-meshheading:16310680-Humans, pubmed-meshheading:16310680-Magnetic Resonance Imaging, pubmed-meshheading:16310680-Male, pubmed-meshheading:16310680-Mental Disorders, pubmed-meshheading:16310680-Psychomotor Agitation, pubmed-meshheading:16310680-Psychotic Disorders, pubmed-meshheading:16310680-Severity of Illness Index, pubmed-meshheading:16310680-Societies, Medical
pubmed:year
2005
pubmed:articleTitle
Grouping for behavioral and psychological symptoms in dementia: clinical and biological aspects. Consensus paper of the European Alzheimer disease consortium.
pubmed:affiliation
Centre Mémoire de Ressources & de Recherche, CHU, Hopital Pasteur, Université de Nice-Sophia Antipolis, 30, Avenue de la Voie Romaine, 06002 Nice cedex 1, France. philippe.robert15@wanadoo.fr
pubmed:publicationType
Journal Article