Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-11-28
pubmed:abstractText
We report the case of a patient with autosomal dominant polycystic kidney disease (ADPKD) and an insufficiency-type fracture of the pelvis. A 60-year-old Japanese woman was admitted because of pain in the right ischium and pubis that began suddenly with no precipitating cause. Computed tomography showed the bony pelvis to be compressed by enlarged dependent kidneys and an enlarged liver. We relieved compression on the pelvic bones by means of transarterial embolization (TAE) to the kidneys and liver after initiation of hemodialysis therapy. The fracture healed gradually after TAE, and the patient could walk 4 months later. In an iliac bone specimen obtained before TAE, cancellous bone was intact, but periosteal and endosteal surfaces of cortical bone showed marked resorption and were irregular. Normally, many ligaments are connected tightly to the periosteal surface, supporting the cortical bone. However, because of extensive surface resorption associated with pressure from enlarged kidneys, connections between ligaments and the periosteal surface presumably became fragile, promoting an insufficiency fracture from unapparent external forces. Thus, ADPKD is a potential cause of insufficiency fracture owing to abnormalities of cortical bone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1523-6838
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
e103-11
pubmed:meshHeading
pubmed-meshheading:16310561-Bone Density, pubmed-meshheading:16310561-Bone Resorption, pubmed-meshheading:16310561-Cysts, pubmed-meshheading:16310561-Embolization, Therapeutic, pubmed-meshheading:16310561-Female, pubmed-meshheading:16310561-Fractures, Spontaneous, pubmed-meshheading:16310561-Hepatomegaly, pubmed-meshheading:16310561-Humans, pubmed-meshheading:16310561-Injections, Intra-Arterial, pubmed-meshheading:16310561-Ischium, pubmed-meshheading:16310561-Kidney, pubmed-meshheading:16310561-Liver, pubmed-meshheading:16310561-Liver Diseases, pubmed-meshheading:16310561-Middle Aged, pubmed-meshheading:16310561-Pelvic Pain, pubmed-meshheading:16310561-Polycystic Kidney, Autosomal Dominant, pubmed-meshheading:16310561-Pressure, pubmed-meshheading:16310561-Pubic Bone, pubmed-meshheading:16310561-Renal Dialysis
pubmed:year
2005
pubmed:articleTitle
Pelvic insufficiency fracture related to autosomal dominant polycystic kidney disease.
pubmed:affiliation
Nephrology Center, Department of Orthopedics, Toranomon Hospital Kajigaya, Kanagawa, Japan. ubara@toranomon.gr.jp
pubmed:publicationType
Journal Article, Case Reports