Source:http://linkedlifedata.com/resource/pubmed/id/16307825
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2006-1-10
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| pubmed:abstractText |
We conducted surveys in 1997 and 2002 to determine the rate, underlying sources and outcome of nosocomial bacteraemia. Blood culture results were reviewed daily. All patients with positive cultures drawn >or=48 h after hospitalization were included in the study and their charts were reviewed. The underlying source of infection was determined by pre-defined clinical and/or microbiological criteria. Patients were followed until discharge or death. In 1997 and 2002, 851 and 857 patient-unique cases of bacteraemia were diagnosed, respectively, excluding contaminants; of these, 228 (27%) and 277 (32%) cases, respectively, were hospital acquired (P<0.05). The overall rate decreased from 7.5 to 7.0 per 1,000 admissions (P<0.001). The sources of bacteraemia in 1997 and 2002, respectively, were: intravascular catheters (36% and 27%, P<0.05), urinary tract (8% and 15%, P<0.05), respiratory tract (5% and 13%, P<0.01) and surgical sites (14% and 4%, P<0.001). In one-third of patients, the source of bacteraemia could not be determined. Only 52% and 54%, respectively, of these patients were discharged alive (difference was not significant). In 1997, Staphylococcus aureus was the most frequent isolate (26%), followed by coagulase-negative Staphylococcus (13%) and Klebsiella pneumoniae (11%). By 2002, the incidence of S. aureus had fallen to 11% (P<0.001), acinetobacter was the single most frequently isolated organism (increased from 6% to 17%) (P<0.001). In-hospital mortality associated with acinetobacter bacteraemia (57%) was significantly higher than that for other organisms (31-43%) (P<0.05). In conclusion, prospective surveys of nosocomial bacteraemias provide valuable information, facilitating the pursuit of successful interventions.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
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| pubmed:issn |
0195-6701
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
62
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
230-6
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| pubmed:meshHeading |
pubmed-meshheading:16307825-Acinetobacter,
pubmed-meshheading:16307825-Acinetobacter Infections,
pubmed-meshheading:16307825-Adolescent,
pubmed-meshheading:16307825-Adult,
pubmed-meshheading:16307825-Aged,
pubmed-meshheading:16307825-Aged, 80 and over,
pubmed-meshheading:16307825-Bacteremia,
pubmed-meshheading:16307825-Catheterization, Central Venous,
pubmed-meshheading:16307825-Child,
pubmed-meshheading:16307825-Child, Preschool,
pubmed-meshheading:16307825-Cross Infection,
pubmed-meshheading:16307825-Female,
pubmed-meshheading:16307825-Hospitals, University,
pubmed-meshheading:16307825-Humans,
pubmed-meshheading:16307825-Incidence,
pubmed-meshheading:16307825-Infant,
pubmed-meshheading:16307825-Infant, Newborn,
pubmed-meshheading:16307825-Israel,
pubmed-meshheading:16307825-Male,
pubmed-meshheading:16307825-Middle Aged,
pubmed-meshheading:16307825-Prospective Studies
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| pubmed:year |
2006
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| pubmed:articleTitle |
Prospective hospital-wide studies of 505 patients with nosocomial bacteraemia in 1997 and 2002.
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| pubmed:affiliation |
Infectious Disease Unit, Shaare Zedek Medical Centre, Jerusalem, Israel.
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| pubmed:publicationType |
Journal Article
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