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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2005-11-24
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|
pubmed:abstractText |
Polyethylene glycol conjugated asparaginase (PEG-ASNase) can be substituted in cases of hypersensitivity to native Escherichia coli asparaginase. We measured asparagine (asn) levels in plasma after a single dose of 2,500 IU/m(2) i.v. PEG-ASNase (Oncaspar) in consolidation treatment of ALL and compared those with data from the previous protocol COALL-05-92. This protocol was similar to COALL-06-97, except that children had been given 45,000 IU/m(2) C-ASNase instead of PEG-ASNase.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:issn |
0300-8630
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pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
217
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
321-6
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|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16307417-Adolescent,
pubmed-meshheading:16307417-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16307417-Asparaginase,
pubmed-meshheading:16307417-Asparagine,
pubmed-meshheading:16307417-Child,
pubmed-meshheading:16307417-Child, Preschool,
pubmed-meshheading:16307417-Chromatography, Ion Exchange,
pubmed-meshheading:16307417-Dose-Response Relationship, Drug,
pubmed-meshheading:16307417-Drug Hypersensitivity,
pubmed-meshheading:16307417-Female,
pubmed-meshheading:16307417-Half-Life,
pubmed-meshheading:16307417-Humans,
pubmed-meshheading:16307417-Infant,
pubmed-meshheading:16307417-Infusions, Intravenous,
pubmed-meshheading:16307417-Male,
pubmed-meshheading:16307417-Multicenter Studies as Topic,
pubmed-meshheading:16307417-Polyethylene Glycols,
pubmed-meshheading:16307417-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:16307417-Randomized Controlled Trials as Topic,
pubmed-meshheading:16307417-Treatment Outcome
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|
pubmed:articleTitle |
Asparagine concentration in plasma after 2,500 IU/m(2) PEG-asparaginase i.v. in children with acute lymphoblastic leukemia.
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pubmed:affiliation |
University Children's Hospital, Pediatric Hematology and Oncology, University of Hamburg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study
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