Linked Life Data

1630436

Source:http://linkedlifedata.com/resource/pubmed/id/1630436

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-8-18
pubmed:abstractText
To evaluate the utility of preoperative irradiation (42.6 Gy) for rectal cancer, we examined histological specimens of surgically resected tumors, which were treated with (36 cases) or without (39 cases) preoperative irradiation. On the basis of the histological findings, irradiated cases were classified into non-effective group (17 cases) and effective group (19 cases). According to quantitative analysis, cancer gland ratio (CGR) was 31.3% in non-irradiated group, 16.6% in non-effective group and 3.6% in effective group, while fibrosis ratio was 19.9%, 34.4% and 38.6%, respectively. The radiotherapy significantly reduced cancer gland and induced fibrosis. Influencing factors of recurrence in rectal cancer, such as depth of invasion, ew, vessel invasion (ly, v) and lymph node involvements were improved in the irradiated group, especially in effective cases, as compared with the non-irradiated group. In conclusion, preoperative irradiation therapy was thought to contribute to control of local recurrence and result in improvement of survival rate by decreasing several risk factors.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0301-4894
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
599-606
pubmed:dateRevised
2011-7-26
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
[Histopathological findings in rectal carcinomas undergoing preoperative irradiation combined with chemotherapy].
pubmed:affiliation
First Department of Surgery, School of Medicine, Chiba University, Japan.
pubmed:publicationType
Journal Article, English Abstract