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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2005-11-23
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pubmed:abstractText |
Tissue atrophy and excessive fibrosis are prominent histologic features of chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation, but the underlying mechanism remains unknown. The current study was undertaken to investigate whether the increase in fibroblasts at the site of pathogenic fibrosis originated from transplanted donor cells in patients with chronic GVHD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4519-27
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16303943-Adult,
pubmed-meshheading:16303943-Antigens, CD34,
pubmed-meshheading:16303943-Biopsy,
pubmed-meshheading:16303943-Chimerism,
pubmed-meshheading:16303943-Chromosomes, Human, Y,
pubmed-meshheading:16303943-Chronic Disease,
pubmed-meshheading:16303943-Dry Eye Syndromes,
pubmed-meshheading:16303943-Female,
pubmed-meshheading:16303943-Fibroblasts,
pubmed-meshheading:16303943-Fibrosis,
pubmed-meshheading:16303943-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:16303943-Graft vs Host Disease,
pubmed-meshheading:16303943-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:16303943-Histone Demethylases,
pubmed-meshheading:16303943-Histone-Lysine N-Methyltransferase,
pubmed-meshheading:16303943-Humans,
pubmed-meshheading:16303943-In Situ Hybridization, Fluorescence,
pubmed-meshheading:16303943-Lacrimal Apparatus,
pubmed-meshheading:16303943-Lacrimal Apparatus Diseases,
pubmed-meshheading:16303943-Male,
pubmed-meshheading:16303943-Microsatellite Repeats,
pubmed-meshheading:16303943-Middle Aged,
pubmed-meshheading:16303943-Neoplasms,
pubmed-meshheading:16303943-Polymerase Chain Reaction,
pubmed-meshheading:16303943-Proteins,
pubmed-meshheading:16303943-RNA, Messenger,
pubmed-meshheading:16303943-Tissue Donors,
pubmed-meshheading:16303943-Transplantation Chimera
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pubmed:year |
2005
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pubmed:articleTitle |
Donor fibroblast chimerism in the pathogenic fibrotic lesion of human chronic graft-versus-host disease.
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pubmed:affiliation |
Institute for Advanced Medical Research, Keio University School of Medicine, Shinanomachi, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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