Source:http://linkedlifedata.com/resource/pubmed/id/16303530
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-11-23
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pubmed:abstractText |
Slit scanning confocal microscopy (Tomey Confoscan P4) was used to evaluate the central cornea of 22 subjects who had been wearing rigid lenses on a long-term, daily wear basis. Anterior and posterior keratocyte densities appeared unaffected by rigid lens wear (P = 0.10 and 0.34 for anterior and posterior keratocyte densities, respectively). Subjects with a previous history of polymethyl methacrylate (PMMA) lens wear showed a reduction in anterior keratocyte density (AKD) (P < 0.0001) and an increased level of haze in the anterior stroma. This may represent previous hypoxic damage. Endothelial cell density (ECD) was unaffected by rigid lens wear (P = 0.36) although an increase in endothelial polymegethism was evident (P < 0.0001). Subjects who had only worn rigid lenses with no history of PMMA lens wear did not show an increase in endothelial polymegethism (P = 0.10). An increased number of microdot opacities compared to the non-lens wearing eye was apparent (P = 0.05). The number of microdot opacities induced by rigid lenses, as reported in this study, appears to be less than that reported by others in respect of soft lenses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1367-0484
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-64
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pubmed:year |
2004
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pubmed:articleTitle |
Confocal microscopy of the corneas of long-term rigid contact lens wearers.
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pubmed:affiliation |
Eurolens Research, Department of Optometry and Neuroscience, UMIST, P.O. Box 88, Manchester M60 1QD, UK.
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pubmed:publicationType |
Journal Article
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