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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0005823,
umls-concept:C0018591,
umls-concept:C0439841,
umls-concept:C0678951,
umls-concept:C0683971,
umls-concept:C1538110,
umls-concept:C1547135,
umls-concept:C1547139,
umls-concept:C1561560,
umls-concept:C1561561
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pubmed:issue |
22
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pubmed:dateCreated |
2005-11-30
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pubmed:abstractText |
Blood pressure (BP) is a heritable trait of major public health concern. The WNK1 and WNK4 genes, which encode proteins in the WNK family of serine-threonine kinases, are involved in renal electrolyte homeostasis. Mutations in the WNK1 and WNK4 genes cause a rare monogenic hypertensive syndrome, pseudohypoaldosteronism type II. We investigated whether polymorphisms in these WNK genes influence BP in the general population.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BodycoteClareC,
pubmed-author:BraundPeterP,
pubmed-author:BurtonPaul RPR,
pubmed-author:CaulfieldMarkM,
pubmed-author:CrossDeborahD,
pubmed-author:GrahamR KRK,
pubmed-author:HayesSaijaS,
pubmed-author:ManessN ONO,
pubmed-author:MunroePatricia BPB,
pubmed-author:NewhouseStephenS,
pubmed-author:RaleighStuart MSM,
pubmed-author:RidgeCathyC,
pubmed-author:SamaniNilesh JNJ,
pubmed-author:SheehanNuala ANA,
pubmed-author:SmithTerryT,
pubmed-author:TobinMartin DMD
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pubmed:issnType |
Electronic
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pubmed:day |
29
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3423-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16301342-Adolescent,
pubmed-meshheading:16301342-Adult,
pubmed-meshheading:16301342-Antihypertensive Agents,
pubmed-meshheading:16301342-Blood Pressure,
pubmed-meshheading:16301342-Blood Pressure Monitoring, Ambulatory,
pubmed-meshheading:16301342-Cardiovascular Diseases,
pubmed-meshheading:16301342-Europe,
pubmed-meshheading:16301342-Family Health,
pubmed-meshheading:16301342-Female,
pubmed-meshheading:16301342-Food Habits,
pubmed-meshheading:16301342-Gene Frequency,
pubmed-meshheading:16301342-Haplotypes,
pubmed-meshheading:16301342-Humans,
pubmed-meshheading:16301342-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:16301342-Male,
pubmed-meshheading:16301342-Middle Aged,
pubmed-meshheading:16301342-Molecular Epidemiology,
pubmed-meshheading:16301342-Polymorphism, Single Nucleotide,
pubmed-meshheading:16301342-Protein-Serine-Threonine Kinases
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pubmed:year |
2005
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pubmed:articleTitle |
Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population.
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pubmed:affiliation |
Department of Health Sciences, University of Leicester, Leicester, England.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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