| pubmed-article:16299074 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C0242694 | lld:lifeskim |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C0242697 | lld:lifeskim |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C0233494 | lld:lifeskim |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C2004454 | lld:lifeskim |
| pubmed-article:16299074 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
| pubmed-article:16299074 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:16299074 | pubmed:dateCreated | 2006-2-1 | lld:pubmed |
| pubmed-article:16299074 | pubmed:abstractText | Permeabilized rat soleus muscle fibers were subjected to rapid shortening/restretch protocols (20% muscle length, 20 ms duration) in solutions with pCa values ranging from 6.5 to 4.5. Force redeveloped after each restretch but temporarily exceeded the steady-state isometric tension reaching a maximum value approximately 2.5 s after relengthening. The relative size of the overshoot was <5% in pCa 6.5 and pCa 4.5 solutions but equaled 17% +/- 4% at pCa 6.0 (approximately half-maximal Ca2+ activation). Muscle stiffness was estimated during pCa 6.0 activations by imposing length steps at different time intervals after repeated shortening/restretch perturbations. Relative stiffness and relative tension were correlated (p < 0.001) during recovery, suggesting that tension overshoots reflect a temporary increase in the number of attached cross-bridges. Rates of tension recovery (k(tr)) correlated (p < 0.001) with the relative residual force prevailing immediately after restretch. Force also recovered to the isometric value more quickly at 5.7 < or = pCa < or = 5.9 than at pCa 4.5 (ANOVA, p < 0.05). These results show that k(tr) measurements underestimate the rate of isometric force development during submaximal Ca2+ activations and suggest that the rate of tension recovery is limited primarily by the availability of actin binding sites. | lld:pubmed |
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| pubmed-article:16299074 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16299074 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16299074 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:16299074 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16299074 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:16299074 | pubmed:issn | 0006-3495 | lld:pubmed |
| pubmed-article:16299074 | pubmed:author | pubmed-author:CampbellKenne... | lld:pubmed |
| pubmed-article:16299074 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16299074 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:16299074 | pubmed:volume | 90 | lld:pubmed |
| pubmed-article:16299074 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16299074 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16299074 | pubmed:pagination | 1288-94 | lld:pubmed |
| pubmed-article:16299074 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:16299074 | pubmed:meshHeading | pubmed-meshheading:16299074... | lld:pubmed |
| pubmed-article:16299074 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16299074 | pubmed:articleTitle | Tension recovery in permeabilized rat soleus muscle fibers after rapid shortening and restretch. | lld:pubmed |
| pubmed-article:16299074 | pubmed:affiliation | Department of Physiology, University of Kentucky, Lexington, Kentucky, USA. k.s.campbell@uky.edu | lld:pubmed |
| pubmed-article:16299074 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16299074 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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