Linked Life Data

16294742

Source:http://linkedlifedata.com/resource/pubmed/id/16294742

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-11-18
pubmed:abstractText
This study sought to assess the effect of a new nano-root filling material, nano-hydroxyapatite polyamide66 (nHA-PA66), on the growth of osteoblast cultured in vitro so as to evaluate its osteoblast-compatibility and potential to be used as root canal filling material. The Dulbecco's Modified Eagle Media (DMEM) leaching liquor of nHA-PA66 was applied to the osteoblasts of the test group while the DMEM itself was applied to control. The MTT assay and flow cytometry were used to evaluate the changes in cell growth and cell cycle. The relative proliferative ratio of different concentrations of nHA-PA66 ranged between 98%-106% without dose-dependent effect. The proportion and time of different subcycle of the two groups were close to each other. nHA-PA66 showed no negative effects on the osteoblasts' growth and cell cycle. These led to the suggestion that nHA-PA66 is not cytotoxic to osteoblast and is a promising material in clinical use.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1001-5515
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1011-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
[Influence of a new nano-root filling material on the proliferation of osteoblast].
pubmed:affiliation
West China College of Stomatology, Sichuan University, Chengdu 610041, China.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't