Linked Life Data

1629179

Source:http://linkedlifedata.com/resource/pubmed/id/1629179

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
1992-8-14
pubmed:abstractText
Previous work has revealed a striking similarity between the sequence of mRNP4, a major mRNA-binding protein of Xenopus laevis oocytes and FRG Y2, a transcription factor specific for Y-box-containing promoters. However, the apparent molecular mass of mRNP4 exceeds by 50-60% the cDNA-deduced molecular mass of FRG Y2. To resolve this discrepancy we have measured the real molecular mass of mRNP4 by sedimentation equilibrium. The molecular mass of mRNP4 closely agrees with that of FRG Y2. We conclude that mRNP4 is identical to FRG Y2 and has a dual function in oocytes. As a DNA-binding protein, mRNP4 stimulates transcription from a specific set of promoters. As a mRNA-binding protein, mRNP4 favors accumulation of the transcripts it contributes to produce.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0021-9258
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
267
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13799-802
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
mRNP4, a major mRNA-binding protein from Xenopus oocytes is identical to transcription factor FRG Y2.
pubmed:affiliation
Centre de Génétique moléculaire, Centre National de la Recherche Scientifique associé à l'Université P. et M. Curie Paris VI, France.
pubmed:publicationType
Journal Article, Comparative Study