Linked Life Data

16288818

Source:http://linkedlifedata.com/resource/pubmed/id/16288818

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-3-28
pubmed:abstractText
This purpose was to discuss optimal reference value for normal glucose tolerance (NGT) at different time points during an oral glucose tolerance test (OGTT) by receiver operating characteristic (ROC) analysis. One thousand seven hundred and forty-six subjects from March 2004 to March 2005 were given 75 g OGTT and the blood samples were collected at 0, 30, 60, 120 and 180 min for glucose measurement. Other demographic data (e.g. age, sex, body mass index, BMI) were also recorded. The status of NGT, impaired glucose tolerance (IGT), impaired fasting glucose (IFG) and DM was determined according to American Diabetes Association (ADA) criteria. IGT and IFG were merged as impaired glucose regulation (IGR). Using IGR as the assumed test, the cutoff values at 0, 30, 60, 120 and 180 min during OGTT for normal reference range were calculated by ROC analysis. The cutoff values were 5.6, 9.5, 10.1, 7.8 and 6.1 mmol/l at 0, 30, 60, 120 and 180 min, respectively, in whole subjects. In addition, we provided the ROC information in age-stratified groups since there are differences among different age groups. When the results of OGTT were considered, the present study provided a reference range value to evaluate the status of glucose tolerance. Because of the heterogeneity of diabetes, further studies are necessity. And the sample collection is continuing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0168-8227
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
88-92
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
The ROC analysis for different time points during oral glucose tolerance test.
pubmed:affiliation
Shanghai Institute of Endocrinology, Department of Endocrinology, Ruijin Hospital, Shanghai Second Medical University, 197 Ruijin 2nd Road, Shanghai 200025, China. pdsucs@163.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't