Source:http://linkedlifedata.com/resource/pubmed/id/16288172
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2005-11-18
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pubmed:abstractText |
Behavioral symptoms are common in dementia, and seem to be more frequent in men than in women. Agitation is frequently responsible for caregiver burn-out and leads to institutionalization. The dramatic increase in the prevalence of Alzheimer's disease and related disorders requires better management of behavior symptoms. Although environmental adaptation has been proposed recently, for many years, psychoactive medications and physical restraints were the primary approach. However, in severely demented patients, both pharmacologic and non-pharmacologic treatments are inoperative. In this situation, alternative pharmacologic approach should be tested. Cyproterone acetate, an antiandrogen and progestative steroid has never been proposed to prevent aggressive behavior in dementia, but its favorable effect is well described in rat and monkey aggressivity.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0035-3787
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1071-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16288172-Aged,
pubmed-meshheading:16288172-Aggression,
pubmed-meshheading:16288172-Alzheimer Disease,
pubmed-meshheading:16288172-Androgen Antagonists,
pubmed-meshheading:16288172-Antipsychotic Agents,
pubmed-meshheading:16288172-Cyproterone,
pubmed-meshheading:16288172-Dementia,
pubmed-meshheading:16288172-Dementia, Vascular,
pubmed-meshheading:16288172-Drug Administration Schedule,
pubmed-meshheading:16288172-Female,
pubmed-meshheading:16288172-Humans,
pubmed-meshheading:16288172-Huntington Disease,
pubmed-meshheading:16288172-Impulsive Behavior,
pubmed-meshheading:16288172-Male,
pubmed-meshheading:16288172-Pilot Projects,
pubmed-meshheading:16288172-Psychomotor Agitation,
pubmed-meshheading:16288172-Severity of Illness Index
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pubmed:year |
2005
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pubmed:articleTitle |
[Preliminary pilot study of cyproterone acetate for the treatment of aggressive behavior associated with severe dementia].
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pubmed:affiliation |
Val d'Escaut, Centre Hospitalier, Valenciennes. dcaparros@nordnet.fr
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pubmed:publicationType |
Journal Article,
English Abstract
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