Linked Life Data

1628755

Source:http://linkedlifedata.com/resource/pubmed/id/1628755

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-8-18
pubmed:abstractText
Previous genetic studies showed that the wild-type function of the lethal (1) optic ganglion reduced (l(1)ogre) gene in Drosophila melanogaster was needed, apparently specifically, for the generation and/or maintenance of postembryonic neuroblasts, i.e., those neuroblasts in the optic formation centers (primordia of the adult optic lobes) and giant neuroblasts scattered over the periphery of cortices of the larval central nervous system (CNS). In the present study temporal and spatial specificity of l(1)ogre expression was investigated by in situ hybridization and also immunofluorescence with polyclonal anti-l(1)ogre antibodies. l(1)ogre protein was detected, as expected, in the optic formation centers and giant neuroblasts in the larval CNS. l(1)ogre expression, however, was not specific to these neuroblasts: expression was also detected in a wide range of tissues including the CNS at many developmental stages. Examination of transcriptional pattern indicates that l(1)ogre is expressed in derivatives of the ectoderm, endoderm, and mesoderm (but not in the germ line) in two developmental contexts: (i) during and shortly after the proliferative phase and (ii) during histolysis of some larval tissues.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
152
pubmed:geneSymbol
l(1)ogre
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
172-83
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The l(1)ogre gene of Drosophila melanogaster is expressed in postembryonic neuroblasts.
pubmed:affiliation
Yale University, Biology Department, New Haven, Connecticut 06511-8112.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't