Source:http://linkedlifedata.com/resource/pubmed/id/16287497
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2005-11-18
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pubmed:abstractText |
Low-grade fibromyxoid sarcoma (LGFMS) is a rare tumor. Reported herein is a case of LGFMS arising in the big toe. The patient was a 58-year-old man who underwent excision of the tumor. The tumor was well-demarcated. Histologically, there were proliferating spindle-shaped tumor cells arranged in a whorled growth pattern, and the stroma showed hyalinized collagen bundles and a myxoid matrix. Nuclear mitotic figures were conspicuous in part. A large rosette-like structure with hyalinized stroma was found, which is characteristic of LGFMS. The differential diagnosis included tumor occurrence in adults; tending to arise in distal extremities; and having bland fibromyxoid histological features, such as fibroma of tendon sheath, low-grade myxofibrosarcoma and acral myxoinflammatory fibroblastic sarcoma. It was not possible to detect the FUS/CREB3L2 and FUS/CREB3L1 fusion genes from the formalin-fixed and paraffin-embedded tissue, although the histological features of the present case were typical of LGFMS. LGFMS may become more common with time, and unique cases may accumulate.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1320-5463
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
802-6
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pubmed:dateRevised |
2007-9-13
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pubmed:meshHeading |
pubmed-meshheading:16287497-Diagnosis, Differential,
pubmed-meshheading:16287497-Fibroma,
pubmed-meshheading:16287497-Humans,
pubmed-meshheading:16287497-Male,
pubmed-meshheading:16287497-Middle Aged,
pubmed-meshheading:16287497-Sarcoma,
pubmed-meshheading:16287497-Soft Tissue Neoplasms,
pubmed-meshheading:16287497-Toes
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pubmed:year |
2005
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pubmed:articleTitle |
Low-grade fibromyxoid sarcoma arising in the big toe.
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pubmed:affiliation |
Department of Pathology, Hirosaki University School of Medicine, Hirosaki, Japan. kusumito@cc.hirosaki-u.ac.jp
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pubmed:publicationType |
Journal Article,
Case Reports
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