Source:http://linkedlifedata.com/resource/pubmed/id/16286306
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2005-11-15
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pubmed:abstractText |
Two cyclic diarylheptanoids, garugamblin-3 (1) and acerogenin L (2), isolated from the MeOH extract of the fruits of Alnus japonica Steud., inhibited human low-density lipoprotein (LDL) oxidation in the thiobarbituric acid-reactive substance assay with IC(50) values of 2.9 and 1.7 microM, respectively, and they also inhibited cell-mediated LDL oxidation more than 5 times more strongly than that of a well-known antioxidant, probucol, at a concentration of 10 microM. Compound (1) had no effect on the anti-atherogenesis in low-density lipoprotein receptor-deficient mice.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1478-6419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-41
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pubmed:dateRevised |
2009-3-23
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pubmed:meshHeading |
pubmed-meshheading:16286306-Alnus,
pubmed-meshheading:16286306-Animals,
pubmed-meshheading:16286306-Heptanes,
pubmed-meshheading:16286306-Humans,
pubmed-meshheading:16286306-Lipoproteins, LDL,
pubmed-meshheading:16286306-Mice,
pubmed-meshheading:16286306-Oxidation-Reduction,
pubmed-meshheading:16286306-Thiobarbituric Acid Reactive Substances
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pubmed:year |
2006
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pubmed:articleTitle |
Cyclic diarylheptanoids inhibit cell mediated low-density lipoprotein oxidation.
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pubmed:affiliation |
Korea Research Institute of Bioscience and Biotechnology, 52 Uendong, Yusung, Taejon 305-600, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Retracted Publication,
Research Support, Non-U.S. Gov't
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