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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2005-11-15
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pubmed:abstractText |
We have previously used the normal lower esophageal sphincter (N-LES) of human organ donors to examine the physiologic signal transduction of lower esophageal sphincter (LES) circular muscle. Now, for the first time, we have obtained a human LES specimen with esophagitis (E-LES) and characterized its pathophysiologic mechanical and inflammatory profiles.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
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pubmed:issn |
0016-5085
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1675-85
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16285965-Dinoprost,
pubmed-meshheading:16285965-Esophageal Sphincter, Lower,
pubmed-meshheading:16285965-Esophagitis, Peptic,
pubmed-meshheading:16285965-F2-Isoprostanes,
pubmed-meshheading:16285965-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:16285965-Humans,
pubmed-meshheading:16285965-Hydrogen Peroxide,
pubmed-meshheading:16285965-Inflammation Mediators,
pubmed-meshheading:16285965-Muscle Tonus,
pubmed-meshheading:16285965-NADPH Oxidase,
pubmed-meshheading:16285965-Oxidants,
pubmed-meshheading:16285965-Oxygen,
pubmed-meshheading:16285965-Platelet Activating Factor,
pubmed-meshheading:16285965-Signal Transduction
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pubmed:year |
2005
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|
pubmed:articleTitle |
Hydrogen peroxide reduces lower esophageal sphincter tone in human esophagitis.
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pubmed:affiliation |
Division of Gastroenterology, Rhode Island Hospital and Brown University, Providence, Rhode Island 02903, USA. piero_biancani@brown.edu
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pubmed:publicationType |
Journal Article,
In Vitro
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