Linked Life Data

16285893

Source:http://linkedlifedata.com/resource/pubmed/id/16285893

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-11-15
pubmed:abstractText
NF-kappaB is a transcription factor of eukaryote, whose family comprises five members in mammals and three in drosophila. Transcription factors of the NF-kappaB family are activated in response to signals that lead to cell growth, differentiation, apoptosis and other events. NF-kappaB takes part in expression of numerous cytokines and adhesion molecules which are critical elements involved in the regulation of immune responses. In this review, we focus on our current understanding of NF-kappaB signal pathway and its role in the innate and adaptive immune responses in which these transcription factors have a key regulatory function. Furthermore we review what is currently known about their effects associated with apoptosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1672-7681
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-50
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
NF-kappaB and its regulation on the immune system.
pubmed:affiliation
Department of Biochemistry, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, China.
pubmed:publicationType
Journal Article, Review