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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-8-17
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pubmed:abstractText |
To examine the relation between increased newborn oxygen requirements and the postnatal rise in cardiac output, we measured left ventricular (LV) output, organ blood flows, and whole-body oxygen consumption using radioactive microspheres in late-gestation sheep fetuses and in the same animals 1 and 4 hours after cesarean section delivery. LV output rose from 264 +/- 23 ml.min-1.kg body wt-1 in fetuses to 444 +/- 33 ml.min-1.kg body wt-1 in lambs at 1 hour after delivery (p less than 0.005) and was unchanged at 4 hours after delivery. This rise in LV output was associated with a more than fourfold increase in the LV flow contribution to tissues situated distal to the ductus arteriosus (fetus, 51 +/- 9 ml.min-1.kg body wt-1; lamb, 226 +/- 22 ml.min-1.kg body wt-1; p less than 0.005), which were mainly perfused by the right ventricle in utero. However, average blood flow to body tissues was similar in fetuses (37 +/- 4 ml.min-1.100 g tissue-1), 1-hour lambs (39 +/- 4 ml.min-1.100 g tissue-1), and 4-hour lambs (40 +/- 5 ml.min-1.100 g tissue-1). Oxygen consumption increased by 58%, from 7.84 +/- 0.43 ml.min-1.kg body wt-1 in fetuses to 12.38 +/- 2.4 ml.min-1.kg body wt-1 in 1-hour lambs (p less than 0.01), and was unchanged in 4-hour lambs.(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-7330
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
443-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1628399-Animals,
pubmed-meshheading:1628399-Animals, Newborn,
pubmed-meshheading:1628399-Blood Circulation,
pubmed-meshheading:1628399-Cardiac Output,
pubmed-meshheading:1628399-Coronary Circulation,
pubmed-meshheading:1628399-Delivery, Obstetric,
pubmed-meshheading:1628399-Female,
pubmed-meshheading:1628399-Fetal Heart,
pubmed-meshheading:1628399-Gestational Age,
pubmed-meshheading:1628399-Oxygen,
pubmed-meshheading:1628399-Oxygen Consumption,
pubmed-meshheading:1628399-Pregnancy,
pubmed-meshheading:1628399-Regional Blood Flow,
pubmed-meshheading:1628399-Sheep
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pubmed:year |
1992
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pubmed:articleTitle |
Indirect relation between rises in oxygen consumption and left ventricular output at birth in lambs.
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pubmed:affiliation |
Centre for Early Human Development, Monash Medical Centre, Clayton, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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