| pubmed-article:16279766 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C0003379 | lld:lifeskim |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C0028426 | lld:lifeskim |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C0184511 | lld:lifeskim |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C1441547 | lld:lifeskim |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:16279766 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:16279766 | pubmed:issue | 23 | lld:pubmed |
| pubmed-article:16279766 | pubmed:dateCreated | 2005-11-10 | lld:pubmed |
| pubmed-article:16279766 | pubmed:abstractText | Analogues of the natural product noscapine were synthesized and their potential as antitumor agents evaluated. The discovery of a novel regioselective O-demethylation facilitated the synthesis of the potent aniline 6, which arrests mammalian cells in the G2/M phase of the cell cycle at 0.1 microM and also affects tubulin polymerization. Aniline 6 is orally bioavailable and is 250-fold more potent than noscapine in reducing cell proliferation in rapidly dividing cells. | lld:pubmed |
| pubmed-article:16279766 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16279766 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16279766 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16279766 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16279766 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16279766 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16279766 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16279766 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:Stricker-Kron... | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:BennaniYousse... | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:AndersonJames... | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:WangJianminJ | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:TingAnthony... | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:PerryRobertR | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:RaberAmyA | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:DanzigJoelJ | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:DentTomT | lld:pubmed |
| pubmed-article:16279766 | pubmed:author | pubmed-author:BoozerSherryS | lld:pubmed |
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| pubmed-article:16279766 | pubmed:author | pubmed-author:PawlowskiGary... | lld:pubmed |
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| pubmed-article:16279766 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16279766 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:16279766 | pubmed:volume | 48 | lld:pubmed |
| pubmed-article:16279766 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16279766 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16279766 | pubmed:pagination | 7096-8 | lld:pubmed |
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| pubmed-article:16279766 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16279766 | pubmed:articleTitle | Identification of novel and improved antimitotic agents derived from noscapine. | lld:pubmed |
| pubmed-article:16279766 | pubmed:affiliation | Athersys, Inc., 3201 Carnegie Avenue, Cleveland, Ohio 44115-2634, USA. janderson@athersys.com | lld:pubmed |
| pubmed-article:16279766 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:16279766 | lld:chembl |
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