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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-11-10
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pubmed:abstractText |
The gold standard clinical trial design is the double-blind, randomized, controlled trial. No standard practice exists for the "unblinding" of trial participants and no legal obligation is placed on investigators to inform participants of their treatment allocation or study results at the end of a trial. Here we document our experiences of unblinding the 2520 Scottish participants in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1740-7745
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
254-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16279148-Aged,
pubmed-meshheading:16279148-Anticholesteremic Agents,
pubmed-meshheading:16279148-Attitude to Health,
pubmed-meshheading:16279148-Cholesterol,
pubmed-meshheading:16279148-Disclosure,
pubmed-meshheading:16279148-Double-Blind Method,
pubmed-meshheading:16279148-Humans,
pubmed-meshheading:16279148-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:16279148-Patient Rights,
pubmed-meshheading:16279148-Patient Selection,
pubmed-meshheading:16279148-Physicians, Family,
pubmed-meshheading:16279148-Placebos,
pubmed-meshheading:16279148-Pravastatin,
pubmed-meshheading:16279148-Prospective Studies,
pubmed-meshheading:16279148-Randomized Controlled Trials as Topic,
pubmed-meshheading:16279148-Research Design,
pubmed-meshheading:16279148-Risk Factors,
pubmed-meshheading:16279148-Vascular Diseases
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pubmed:year |
2005
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pubmed:articleTitle |
Unblinding of trial participants to their treatment allocation: lessons from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).
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pubmed:affiliation |
Clinical Trials Unit, Glasgow Royal Infirmary, Glasgow, UK.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Multicenter Study
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