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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2005-11-8
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pubmed:abstractText |
There is increasing evidence that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) reduce cardiovascular and cerebrovascular events through anti-inflammatory, plaque stabilization, and neuroprotective effects independent of lipid lowering. This study was designed to investigate whether statin use reduces the incidence of perioperative stroke and mortality among patients undergoing carotid endarterectomy (CEA).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0741-5214
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pubmed:author |
pubmed-author:BrookeBenjamin SBS,
pubmed-author:BuckDonaldD,
pubmed-author:CoonAlexanderA,
pubmed-author:FreischlagJulie AJA,
pubmed-author:HellerJenniferJ,
pubmed-author:JainShamikS,
pubmed-author:McGirtMatthew JMJ,
pubmed-author:PerlerBruce ABA,
pubmed-author:RoseboroughGlen SGS,
pubmed-author:TamargoRafael JRJ,
pubmed-author:WilliamsGeorge MGM,
pubmed-author:WoodworthGraeme FGF
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
829-36; discussion 836-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16275430-Aged,
pubmed-meshheading:16275430-Carotid Stenosis,
pubmed-meshheading:16275430-Endarterectomy, Carotid,
pubmed-meshheading:16275430-Female,
pubmed-meshheading:16275430-Follow-Up Studies,
pubmed-meshheading:16275430-Humans,
pubmed-meshheading:16275430-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:16275430-Male,
pubmed-meshheading:16275430-Multivariate Analysis,
pubmed-meshheading:16275430-Perioperative Care,
pubmed-meshheading:16275430-Postoperative Complications,
pubmed-meshheading:16275430-Retrospective Studies,
pubmed-meshheading:16275430-Risk Factors,
pubmed-meshheading:16275430-Stroke,
pubmed-meshheading:16275430-Survival Rate,
pubmed-meshheading:16275430-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomy.
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pubmed:affiliation |
Department of Neurosurgery, the Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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