Source:http://linkedlifedata.com/resource/pubmed/id/16275186
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
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| pubmed:dateCreated |
2005-11-8
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| pubmed:abstractText |
Because late vessel failure has been speculated as a possible limitation of vascular brachytherapy, we conducted a prospective clinical evaluation at 6, 12, 24, and 36 months of follow-up after irradiation with strontium-90/yttrium-90 for in-stent restenosis, regardless of the patient's symptomatic status. We report complete 3-year follow-up data for 106 consecutive patients. The cumulative rate of death at 6, 12, 24, and 36 months was 0.9%, 0.9%, 0.9%, and 1.9% respectively. The corresponding rates for acute ST-elevation myocardial infarction were 2.8%, 4.7%, 4.7%, and 4.7%, respectively. The cumulative rate of late thrombotic occlusion at 6, 12, 24, and 36 months was 3.8%, 4.7%, 4.7%, and 4.7%, respectively. The corresponding rates of target lesion revascularization and target vessel revascularization were 8.5% and 12.3% (p = 0.046), 14.2% (p = 0.157) and 18.0% (p = 0.046), 12.3% and 18.9% (p = 0.008), and 21.7% (p = 0.083) and 29.2% (p = 0.005), respectively. The cumulative rate of all major adverse cardiovascular events at 6, 12, 24, and 36 months was 16.1%, 24.5% (p = 0.003), 27.4% (p = 0.083), and 35.8% (p = 0.003), respectively. In conclusion, these results indicate a delayed and, even in the third year after the index procedure, continued restenotic process after beta irradiation of in-stent restenotic lesions.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
0002-9149
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| pubmed:author |
pubmed-author:BaierlVerenaV,
pubmed-author:BaumgartnerSimoneS,
pubmed-author:DühmkeEckhartE,
pubmed-author:HaimerlWolfgangW,
pubmed-author:KönigAndreasA,
pubmed-author:KlaussVolkerV,
pubmed-author:KrötzFlorianF,
pubmed-author:LeibigMarcusM,
pubmed-author:PöllingerBarbaraB,
pubmed-author:RieberJohannesJ,
pubmed-author:SchieleThomas MTM,
pubmed-author:SiebertUweU,
pubmed-author:SohnHae-YoungHY,
pubmed-author:TheisenKarlK
|
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
96
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1399-403
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| pubmed:meshHeading |
pubmed-meshheading:16275186-Aged,
pubmed-meshheading:16275186-Blood Vessel Prosthesis Implantation,
pubmed-meshheading:16275186-Brachytherapy,
pubmed-meshheading:16275186-Coronary Angiography,
pubmed-meshheading:16275186-Coronary Restenosis,
pubmed-meshheading:16275186-Disease-Free Survival,
pubmed-meshheading:16275186-Female,
pubmed-meshheading:16275186-Follow-Up Studies,
pubmed-meshheading:16275186-Humans,
pubmed-meshheading:16275186-Male,
pubmed-meshheading:16275186-Middle Aged,
pubmed-meshheading:16275186-Postoperative Complications,
pubmed-meshheading:16275186-Prospective Studies,
pubmed-meshheading:16275186-Radiopharmaceuticals,
pubmed-meshheading:16275186-Stents,
pubmed-meshheading:16275186-Strontium Radioisotopes,
pubmed-meshheading:16275186-Treatment Outcome,
pubmed-meshheading:16275186-Yttrium Radioisotopes
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| pubmed:year |
2005
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| pubmed:articleTitle |
Three-year clinical follow-up after strontium-90/yttrium-90 beta-irradiation for the treatment of in-stent coronary restenosis.
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| pubmed:affiliation |
Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany.
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| pubmed:publicationType |
Journal Article
|