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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
39
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pubmed:dateCreated |
2005-11-7
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pubmed:abstractText |
Activated pancreatic stellate cells (PSCs) are implicated in the pathogenesis of pancreatic fibrosis and inflammation. Endothelin-1 (ET-1), which acts through G-protein coupled ET(A) and ET(B) receptors, has several biological activities. We here examined the ability of ET-1 to affect the cell functions of PSCs and the underlying molecular mechanisms.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1007-9327
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
21
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|
pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6144-51
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:16273641-Animals,
pubmed-meshheading:16273641-Cell Movement,
pubmed-meshheading:16273641-Cells, Cultured,
pubmed-meshheading:16273641-Endothelin-1,
pubmed-meshheading:16273641-Fibrosis,
pubmed-meshheading:16273641-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:16273641-Male,
pubmed-meshheading:16273641-Pancreas,
pubmed-meshheading:16273641-Protein-Serine-Threonine Kinases,
pubmed-meshheading:16273641-Rats,
pubmed-meshheading:16273641-Rats, Wistar,
pubmed-meshheading:16273641-Receptors, Endothelin,
pubmed-meshheading:16273641-rho-Associated Kinases
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pubmed:year |
2005
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pubmed:articleTitle |
Endothelin-1 stimulates contraction and migration of rat pancreatic stellate cells.
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pubmed:affiliation |
Division of Gastro-enterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan. amasamune@int3.med.tohoku.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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