Linked Life Data

16272808

Source:http://linkedlifedata.com/resource/pubmed/id/16272808

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2005-11-7
pubmed:abstractText
We studied a reverse phase HPLC method employing a simple acetonitrile: 0.1% phosphoric acid aqueous solution gradient as the mobile phase for the determination of furanocoumarin (FC) derivatives, such as bergamottin (BG) and 6',7'-dihydroxybergamottin (DHB), using UV detection. Anthracene was added to samples as an internal standard. A Capcell Pak SG-Phenyl column (4.6 mm [inner diameter] x 25 cm; particle size 5 mm; Shiseido) was used, and the flow rate was set at a constant 1 ml/min. A photodiode array detector was used because it reveals the characteristic UV-absorption spectrum of FCs, commonly with 311 nm as the maximum wavelength. Furanocoumarin derivatives in pomelo juice (PJ) were detected by the method and compared with those in grapefruit juice (GJ) and orange juice (OJ). GJ contained 3 kinds of FCs, BG, DHB and bergaptol (BT). OJ had no FCs. On the other hand, PJ contained 8 kinds of FCs including BT, BG and DHB. This FC detection system may be effective for identifying foods and beverages that interact adversely with drugs.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0031-6903
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
875-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
[Comprehensive determination of furanocoumarin derivatives in citrus juice by high performance liquid chromatography].
pubmed:affiliation
Clinical Pharmaceutics Laboratory, Department of Pharmaceutics, Meiji Pharmaceutical University, Tokyo, Japan. uesawa@my-pharm.ac.jp
pubmed:publicationType
Journal Article, Comparative Study, English Abstract