|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
18
|
|
pubmed:dateCreated |
2005-11-3
|
|
pubmed:abstractText |
Transplantation of endothelial progenitor cells has been proposed as a potential strategy for therapeutic revascularization. However, the limited endogenous cell pool and the related technical difficulties constitute clinically important disadvantages to autologous transplantation. In this study we investigated whether fully differentiated endothelial cells (ECs) modified with gene transfer of Id1, a helix-loop-helix transcription factor involved in angiogenesis, have the potential to contribute to therapeutic angiogenesis.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
112
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2840-50
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16267257-3' Untranslated Regions,
pubmed-meshheading:16267257-5' Untranslated Regions,
pubmed-meshheading:16267257-Animals,
pubmed-meshheading:16267257-Base Sequence,
pubmed-meshheading:16267257-Cell Division,
pubmed-meshheading:16267257-Cells, Cultured,
pubmed-meshheading:16267257-DNA Primers,
pubmed-meshheading:16267257-Embryo, Mammalian,
pubmed-meshheading:16267257-Endothelium, Vascular,
pubmed-meshheading:16267257-Gene Transfer Techniques,
pubmed-meshheading:16267257-Genetic Vectors,
pubmed-meshheading:16267257-Humans,
pubmed-meshheading:16267257-Inhibitor of Differentiation Protein 1,
pubmed-meshheading:16267257-Mice,
pubmed-meshheading:16267257-Molecular Sequence Data,
pubmed-meshheading:16267257-Neovascularization, Physiologic,
pubmed-meshheading:16267257-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16267257-Sendai virus,
pubmed-meshheading:16267257-Umbilical Veins
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Id1 gene transfer confers angiogenic property on fully differentiated endothelial cells and contributes to therapeutic angiogenesis.
|
|
pubmed:affiliation |
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan. nkanako@gpo.kumamoto-u.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
