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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
11
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pubmed:dateCreated |
2005-11-3
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pubmed:abstractText |
From 20-50% of patients with acute myeloid leukemia (AML) are primarily resistant to induction chemotherapy. It has previously been shown that resistance to the first cycle of induction chemotherapy is an independent prognostic factor. We investigated whether resistance to chemotherapy be represented by gene-expression profiles, and which genes are associated with resistance.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1592-8721
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pubmed:author |
pubmed-author:BullingerLarsL,
pubmed-author:CarioGunnarG,
pubmed-author:DöhnerHartmutH,
pubmed-author:GanserArnoldA,
pubmed-author:HeilGerhardG,
pubmed-author:HeuserMichaelM,
pubmed-author:KrauterJuergenJ,
pubmed-author:SchlegelbergerBrigitteB,
pubmed-author:SteinemannDorisD,
pubmed-author:TauscherMarcelM,
pubmed-author:WingenLuzie ULU,
pubmed-author:von NeuhoffNilsN
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pubmed:issnType |
Electronic
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pubmed:volume |
90
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1484-92
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16266895-Adolescent,
pubmed-meshheading:16266895-Adult,
pubmed-meshheading:16266895-Aged,
pubmed-meshheading:16266895-Antineoplastic Agents,
pubmed-meshheading:16266895-Drug Resistance, Neoplasm,
pubmed-meshheading:16266895-Female,
pubmed-meshheading:16266895-Gene Expression Profiling,
pubmed-meshheading:16266895-Genetic Markers,
pubmed-meshheading:16266895-Humans,
pubmed-meshheading:16266895-Leukemia, Myeloid, Acute,
pubmed-meshheading:16266895-Male,
pubmed-meshheading:16266895-Middle Aged,
pubmed-meshheading:16266895-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16266895-Survival Analysis
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pubmed:year |
2005
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pubmed:articleTitle |
Gene-expression profiles and their association with drug resistance in adult acute myeloid leukemia.
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pubmed:affiliation |
Department of Hematology, Hemostaseology and Oncology, Hannover Medical School, Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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