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rdf:type |
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lifeskim:mentions |
umls-concept:C0008972,
umls-concept:C0012854,
umls-concept:C0017366,
umls-concept:C0019704,
umls-concept:C0042210,
umls-concept:C0079160,
umls-concept:C0449560,
umls-concept:C0870134,
umls-concept:C1519249,
umls-concept:C1527178,
umls-concept:C1533585,
umls-concept:C1705938,
umls-concept:C1709630
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pubmed:issue |
14
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pubmed:dateCreated |
2005-11-21
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pubmed:abstractText |
A potent DNA vaccine against HIV, combining a vector that takes advantage of the segregation and compartmentalization effect of bovine papilloma virus E2 protein with MultiHIV insert, expressing a fusion gene coding for the non-structural and structural proteins was developed and tested for immunogenicity in mice and humans.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AIDS Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, nef,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, rev,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, tat,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Vaccines, DNA,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Nonstructural Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Structural Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/nef Gene Products, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/rev Gene Products, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/tat Gene Products, Human...
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1286-4579
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1405-13
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16257560-AIDS Vaccines,
pubmed-meshheading:16257560-Animals,
pubmed-meshheading:16257560-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16257560-Clinical Trials, Phase I as Topic,
pubmed-meshheading:16257560-Clinical Trials, Phase II as Topic,
pubmed-meshheading:16257560-Consensus Sequence,
pubmed-meshheading:16257560-Disease Models, Animal,
pubmed-meshheading:16257560-Epitopes,
pubmed-meshheading:16257560-Gene Products, nef,
pubmed-meshheading:16257560-Gene Products, rev,
pubmed-meshheading:16257560-Gene Products, tat,
pubmed-meshheading:16257560-Genetic Vectors,
pubmed-meshheading:16257560-HIV Antibodies,
pubmed-meshheading:16257560-HIV Infections,
pubmed-meshheading:16257560-HIV-1,
pubmed-meshheading:16257560-Humans,
pubmed-meshheading:16257560-Mice,
pubmed-meshheading:16257560-Mice, Inbred BALB C,
pubmed-meshheading:16257560-Models, Animal,
pubmed-meshheading:16257560-Recombinant Fusion Proteins,
pubmed-meshheading:16257560-Vaccines, DNA,
pubmed-meshheading:16257560-Viral Nonstructural Proteins,
pubmed-meshheading:16257560-Viral Structural Proteins,
pubmed-meshheading:16257560-nef Gene Products, Human Immunodeficiency Virus,
pubmed-meshheading:16257560-rev Gene Products, Human Immunodeficiency Virus,
pubmed-meshheading:16257560-tat Gene Products, Human Immunodeficiency Virus
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pubmed:year |
2005
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pubmed:articleTitle |
A DNA HIV-1 vaccine based on a fusion gene expressing non-structural and structural genes of consensus sequence of the A-C subtypes and the ancestor sequence of the F-H subtypes. Preclinical and clinical studies.
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pubmed:affiliation |
Institute of Medical Technology, University of Tampere, Biokatu 8, 33520 Tampere, Finland. kai.krohn@uta.fi
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pubmed:publicationType |
Journal Article
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